BDBM50343151 CHEMBL1773184::N1-(benzo[d][1,3]dioxol-5-ylmethyl)-N2-(1-(4-phenylpiperazin-1-yl)-1-(thiophen-2-yl)propan-2-yl)oxalamide

SMILES CC(NC(=O)C(=O)NCc1ccc2OCOc2c1)C(N1CCN(CC1)c1ccccc1)c1cccs1

InChI Key InChIKey=GCRZWEPCVNKKLG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343151   

TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343151(N1-(benzo[d][1,3]dioxol-5-ylmethyl)-N2-(1-(4-pheny...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB preincubated with compound for 30 mins before pNPP substrate addition by micropl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343151(N1-(benzo[d][1,3]dioxol-5-ylmethyl)-N2-(1-(4-pheny...)
Affinity DataIC50: 3.04E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed