BDBM50343430 CHEMBL1775036::N-(3-Chlorophenyl)-1-(2-chloro-2-phenylethyl)-6-[(2-morpholin-4-ylethyl)thio]-1H-pyrazolo[3,4-d]pyrimidin-4-amine

SMILES ClC(Cn1ncc2c(Nc3cccc(Cl)c3)nc(SCCN3CCOCC3)nc12)c1ccccc1

InChI Key InChIKey=UWCATRMYQSEPKR-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50343430   

TargetTyrosine-protein kinase ABL1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50343430(N-(3-Chlorophenyl)-1-(2-chloro-2-phenylethyl)-6-[(...)
Affinity DataKi:  120nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50343430(N-(3-Chlorophenyl)-1-(2-chloro-2-phenylethyl)-6-[(...)
Affinity DataKi:  120nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50343430(N-(3-Chlorophenyl)-1-(2-chloro-2-phenylethyl)-6-[(...)
Affinity DataKi:  180nMAssay Description:Inhibition of human recombinant Abl kinase using [gamma-32P]ATP as substrate by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50343430(N-(3-Chlorophenyl)-1-(2-chloro-2-phenylethyl)-6-[(...)
Affinity DataKi:  190nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50343430(N-(3-Chlorophenyl)-1-(2-chloro-2-phenylethyl)-6-[(...)
Affinity DataKi:  190nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50343430(N-(3-Chlorophenyl)-1-(2-chloro-2-phenylethyl)-6-[(...)
Affinity DataKi:  290nMAssay Description:Inhibition of human recombinant src kinase using KVEKIGEGTYGVVYK as substrate by filter binding assay in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed