BDBM50343486 4-(4-(4-fluorophenyl)-2-((R)-methylsulfinyl)-1H-imidazol-5-yl)-N-((S)-3-methylbutan-2-yl)pyridin-2-amine::CHEMBL1773510

SMILES CC(C)[C@H](C)Nc1cc(ccn1)-c1nc([nH]c1-c1ccc(F)cc1)[S@@](C)=O

InChI Key InChIKey=ZBJPQFVITVEFPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343486   

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343486(4-(4-(4-fluorophenyl)-2-((R)-methylsulfinyl)-1H-im...)
Affinity DataIC50: 200nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343486(4-(4-(4-fluorophenyl)-2-((R)-methylsulfinyl)-1H-im...)
Affinity DataIC50: 19nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed