BDBM50343494 (S)-2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-imidazol-5-yl)pyridin-2-yl)acetamide::CHEMBL1773431

SMILES C[S@](=O)c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC(=O)Cc2ccc(F)cc2)c1

InChI Key InChIKey=CHQVABOBZWQZHI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50343494   

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343494((S)-2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-...)
Affinity DataIC50: 7.53E+3nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343494((S)-2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-...)
Affinity DataIC50: 5.55E+3nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343494((S)-2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-...)
Affinity DataIC50: 141nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343494((S)-2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-...)
Affinity DataIC50: 69nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed