BDBM50343496 (S)-N-(4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-imidazol-5-yl)pyridin-2-yl)acetamide::CHEMBL1773428

SMILES CC(=O)Nc1cc(ccn1)-c1nc([nH]c1-c1ccc(F)cc1)[S@](C)=O

InChI Key InChIKey=FSGQSNMSKKPBHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343496   

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343496((S)-N-(4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H...)
Affinity DataIC50: 197nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343496((S)-N-(4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H...)
Affinity DataIC50: 403nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed