BDBM50343525 2-(4-bromo-3-(N-p-tolylsulfamoyl)benzamido)benzoic acid::CHEMBL1774306

SMILES Cc1ccc(NS(=O)(=O)c2cc(ccc2Br)C(=O)Nc2ccccc2C(O)=O)cc1

InChI Key InChIKey=SKGKEBUDJVJJDK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50343525   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50343525(2-(4-bromo-3-(N-p-tolylsulfamoyl)benzamido)benzoic...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant 5-LO in cell-free system assessed as inhibition of LTB4 production after 10 mins by RP-HPLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50343525(2-(4-bromo-3-(N-p-tolylsulfamoyl)benzamido)benzoic...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of 5-LO in human polymorphonuclear leukocytes assessed as inhibition of LTB4 production after 10 mins by RP-HPLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50343525(2-(4-bromo-3-(N-p-tolylsulfamoyl)benzamido)benzoic...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human microsomal PGES1 in cell-free system assessed as inhibition of conversion of PGH2 to PGE2 by HPLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed