BDBM50343534 (R)-2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)-2-(naphthalen-1-yl)acetic acid::CHEMBL1774174

SMILES Cc1cccc(Nc2cc(Cl)nc(S[C@@H](C(O)=O)c3cccc4ccccc34)n2)c1C

InChI Key InChIKey=KSKMNZFKRMRMDJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343534   

TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50343534((R)-2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimid...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human microsomal PGES1 in cell-free system assessed as inhibition of conversion of PGH2 to PGE2 by HPLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed