BDBM50343727 (S)-5-chloro-2-(1-(5-fluoropyridin-2-yl)ethylamino)-6-(5-methyl-1H-pyrazol-3-ylamino)nicotinonitrile::CHEMBL1773082

SMILES C[C@H](Nc1nc(Nc2cc(C)n[nH]2)c(Cl)cc1C#N)c1ccc(F)cn1

InChI Key InChIKey=DWBXDMFMVZHVSB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343727   

TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50343727((S)-5-chloro-2-(1-(5-fluoropyridin-2-yl)ethylamino...)
Affinity DataIC50: 3nMAssay Description:Inhibition of JAK2 after 60 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50343727((S)-5-chloro-2-(1-(5-fluoropyridin-2-yl)ethylamino...)
Affinity DataIC50: 21nMAssay Description:Inhibition of JAK3 after 60 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed