BDBM50343890 4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-N-(pyridin-2-yl)cubyl-1-carboxamide::CHEMBL1774991

SMILES COc1ccccc1N1CCN(CCN(C(=O)C23C4C5C2C2C3C4C52I)c2ccccn2)CC1

InChI Key InChIKey=YTOGOMGUCNEXIR-UHFFFAOYSA-N

Data  8 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50343890   

Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataIC50: 2.59nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  1.11nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  78nMAssay Description:Inhibition of adrenergic alpha1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  98nMAssay Description:Inhibition of adrenergic Alpha-1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  121nMAssay Description:Inhibition of 5HT1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  161nMAssay Description:Inhibition of 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  185nMAssay Description:Inhibition of adrenergic Alpha-1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343890(4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)eth...)
Affinity DataKi:  329nMAssay Description:Inhibition of dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed