BDBM50343895 CHEMBL1774996::N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-iodo-N-(pyridin-2-yl)bicyclo[2.2.2]octane-1-carboxamide

SMILES Oc1ccccc1N1CCN(CCN(C(=O)C23CCC(I)(CC2)CC3)c2ccccn2)CC1

InChI Key InChIKey=CLKRZINIDXJKNI-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343895   

Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343895(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataIC50: 4.57nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343895(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  1.95nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed