BDBM50344055 8-Ethoxy-3-phenylcoumarin::CHEMBL1777843

SMILES CCOc1cccc2cc(-c3ccccc3)c(=O)oc12

InChI Key InChIKey=JWPFCIXQOFVAHQ-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50344055   

TargetPolyphenol oxidase 2(White button mushroom)
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50344055(8-Ethoxy-3-phenylcoumarin | CHEMBL1777843)
Affinity DataIC50: 2.07E+6nMAssay Description:Inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate measured for 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50344055(8-Ethoxy-3-phenylcoumarin | CHEMBL1777843)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human adenosine receptor A2B expressed in CHO cells assessed as suppression of NECA-induced decrease of cAMP accumulation by G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50344055(8-Ethoxy-3-phenylcoumarin | CHEMBL1777843)
Affinity DataKi:  3.93E+3nMAssay Description:Displacement of [3H]HEMADO from human adenosine A3 receptor expressed in CHO cells measured by radioligand competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A1(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50344055(8-Ethoxy-3-phenylcoumarin | CHEMBL1777843)
Affinity DataKi:  2.21E+4nMAssay Description:Displacement of [3H]CCPA from human adenosine receptor A1 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50344055(8-Ethoxy-3-phenylcoumarin | CHEMBL1777843)
Affinity DataKi:  2.25E+4nMAssay Description:Displacement of [3H]HEMADO from human adenosine receptor A3 expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50344055(8-Ethoxy-3-phenylcoumarin | CHEMBL1777843)
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of radioligand from human adenosine receptor A2B expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50344055(8-Ethoxy-3-phenylcoumarin | CHEMBL1777843)
Affinity DataKi:  5.50E+4nMAssay Description:Displacement of [3H]NECA from human adenosine receptor A2A expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed