BDBM50344062 6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin::CHEMBL1777849

SMILES Oc1ccc(cc1)-c1cc2cc(Br)cc(O)c2oc1=O

InChI Key InChIKey=JRNZENXEHYOMCY-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50344062   

TargetPolyphenol oxidase 2(White button mushroom)
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50344062(6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin | C...)
Affinity DataIC50: 2.15E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate measured for 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50344062(6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin | C...)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine substrate by fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50344062(6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin | C...)
Affinity DataIC50: 2.07E+4nMAssay Description:Inhibition of human recombinant MAO-A using p-tyramine substrate by fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50344062(6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin | C...)
Affinity DataKi:  1.89E+5nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate by Lineweaver-Burk double reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed