BDBM50344447 CHEMBL1780016::methyl-5-(diethylcarbamoyl)-4-methyl-2-(2-m-tolylquinoline-4-carboxamido)thiophene-3-carboxylate

SMILES CCN(CC)C(=O)c1sc(NC(=O)c2cc(nc3ccccc23)-c2cccc(C)c2)c(C(=O)OC)c1C

InChI Key InChIKey=CWKMYTRJRIARRB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344447   

TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344447(methyl-5-(diethylcarbamoyl)-4-methyl-2-(2-m-tolylq...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344447(methyl-5-(diethylcarbamoyl)-4-methyl-2-(2-m-tolylq...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed