BDBM50344501 (1S,5S)-8-(4-fluorophenylsulfonyl)-3-(5-methyl-6-(2-methylpyridin-3-yloxy)pyrimidin-4-yloxy)-8-azabicyclo[3.2.1]octane::CHEMBL1778239

SMILES Cc1ncccc1Oc1ncnc(OC2C[C@@H]3CC[C@@H](C2)N3S(=O)(=O)c2ccc(F)cc2)c1C

InChI Key InChIKey=JKYHHGCQASLIAE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344501   

TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344501((1S,5S)-8-(4-fluorophenylsulfonyl)-3-(5-methyl-6-(...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344501((1S,5S)-8-(4-fluorophenylsulfonyl)-3-(5-methyl-6-(...)
Affinity DataEC50:  350nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed