BDBM50344507 6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo[3.2.1]octan-3-yloxy)-5-methyl-N-(2-methylpyridin-3-yl)pyrimidin-4-amine::CHEMBL1778244

SMILES Cc1ncccc1Nc1ncnc(OC2C[C@@H]3CC[C@@H](C2)N3S(=O)(=O)C2CC2)c1C

InChI Key InChIKey=OHBYIWNTLDJBPZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344507   

TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344507(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo[3....)
Affinity DataEC50:  54nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344507(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo[3....)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed