BDBM50344509 2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo[3.2.1]octan-3-yloxy)-5-methylpyrimidin-4-ylamino)-5-fluorobenzonitrile::CHEMBL1778246

SMILES Cc1c(Nc2ccc(F)cc2C#N)ncnc1OC1C[C@@H]2CC[C@@H](C1)N2S(=O)(=O)C1CC1

InChI Key InChIKey=SQAOFWPVTLZDNS-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344509   

TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344509(2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo...)
Affinity DataEC50:  34nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344509(2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo...)
Affinity DataEC50:  820nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed