BDBM50344513 (1R,5R)-8-(cyclopropylsulfonyl)-3-(5-methyl-6-(2-methylpyridin-3-yloxy)pyrimidin-4-yloxy)-8-azabicyclo[3.2.1]oct-6-ene::CHEMBL1778251

SMILES Cc1ncccc1Oc1ncnc(OC2C[C@@H]3C=C[C@@H](C2)N3S(=O)(=O)C2CC2)c1C

InChI Key InChIKey=KCNFGDJUPGBTGX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344513   

TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344513((1R,5R)-8-(cyclopropylsulfonyl)-3-(5-methyl-6-(2-m...)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344513((1R,5R)-8-(cyclopropylsulfonyl)-3-(5-methyl-6-(2-m...)
Affinity DataEC50:  240nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed