BDBM50344533 4-(2-(3-isopropylphenylamino)benzo[d]oxazol-5-yloxy)-N-(2-morpholinoethyl)picolinamide::CHEMBL1778402

SMILES CC(C)c1cccc(Nc2nc3cc(Oc4ccnc(c4)C(=O)NCCN4CCOCC4)ccc3o2)c1

InChI Key InChIKey=FZNVJIJNWWXKAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344533   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344533(4-(2-(3-isopropylphenylamino)benzo[d]oxazol-5-ylox...)
Affinity DataIC50: 140nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed