BDBM50344547 4-(2-(2-fluorophenylamino)benzo[d]oxazol-5-yloxy)-N-methylpicolinamide::CHEMBL1778292

SMILES CNC(=O)c1cc(Oc2ccc3oc(Nc4ccccc4F)nc3c2)ccn1

InChI Key InChIKey=NHCJCHFTBCCHIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344547   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344547(4-(2-(2-fluorophenylamino)benzo[d]oxazol-5-yloxy)-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed