BDBM50344569 CHEMBL1778447::N-(4-bromo-6-(3-methylureido)pyridin-2-ylcarbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide

SMILES Cc1cc(sc1CCOC)S(=O)(=O)NC(=O)Nc2cc(cc(n2)NC(=O)NC)Br

InChI Key InChIKey=OKYOPMCSUZGIPB-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344569   

TargetFructose-1,6-bisphosphatase 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50344569(N-(4-bromo-6-(3-methylureido)pyridin-2-ylcarbamoyl...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human liver fructose-1,6-bisphosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50344569(N-(4-bromo-6-(3-methylureido)pyridin-2-ylcarbamoyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse liver fructose-1,6-bisphosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed