BDBM50344657 1-(2-(3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yloxy)ethyl)urea::CHEMBL1779195::US9126931, 38

SMILES CC1(C)c2[nH]c3cc(ccc3c2C(=O)c2ccc(OCCNC(N)=O)cc12)C#N

InChI Key InChIKey=BGLYSKVZXDMUDZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344657   

TargetALK tyrosine kinase receptor(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM50344657(1-(2-(3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-...)
Affinity DataIC50: 26.2nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM50344657(1-(2-(3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-...)
Affinity DataIC50: 26.2nMAssay Description:Inhibition of ALK assessed as biotin-EGPWLEEEEEAYGWMDF peptide phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed