BDBM50344670 6,8-dichloro-4-((5-(2-methylthiazol-4-yl)-4-(3,3,3-trifluoropropyl)-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL1779218

SMILES Cc1nc(cs1)-c1nnc(CN2C(=O)COc3c(Cl)cc(Cl)cc23)n1CCC(F)(F)F

InChI Key InChIKey=BCLVNWONOUTPTI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344670   

TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50344670(6,8-dichloro-4-((5-(2-methylthiazol-4-yl)-4-(3,3,3...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-Glucose uptake using [14C]-methyl glucopyranoside after 60 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed