BDBM50344675 6-chloro-4-((5-(5-chloropyridin-2-yl)-4-(3,3,3-trifluoropropyl)-4H-1,2,4-triazol-3-yl)methyl)-8-nitro-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL1779223

SMILES [O-][N+](=O)c1cc(Cl)cc2N(Cc3nnc(-c4ccc(Cl)cn4)n3CCC(F)(F)F)C(=O)COc12

InChI Key InChIKey=CYGGWTOVNXMRNL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344675   

TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50344675(6-chloro-4-((5-(5-chloropyridin-2-yl)-4-(3,3,3-tri...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-Glucose uptake using [14C]-methyl glucopyranoside after 60 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed