BDBM50344682 6-chloro-4-((5-(3-methylpyridin-2-yl)-4-propyl-4H-1,2,4-triazol-3-yl)methyl)-8-nitro-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL1779342

SMILES CCCn1c(CN2C(=O)COc3c2cc(Cl)cc3[N+]([O-])=O)nnc1-c1ncccc1C

InChI Key InChIKey=UZKJIBCBXAWJTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344682   

TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50344682(6-chloro-4-((5-(3-methylpyridin-2-yl)-4-propyl-4H-...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-Glucose uptake using [14C]-methyl glucopyranoside after 60 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed