BDBM50344799 CHEMBL1779732::N-(4-(aminomethyl)-2,6-dimethylphenyl)-5-(2,5-dichlorophenyl)furan-2-carboxamide

SMILES Cc1cc(CN)cc(C)c1NC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl

InChI Key InChIKey=QWJOPXDAQCDRRM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50344799   

TargetSphingosine 1-phosphate receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50344799(N-(4-(aminomethyl)-2,6-dimethylphenyl)-5-(2,5-dich...)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at S1P4 receptor in human U2OS cells expressing EDG6-linked GAL4-VP16 transcription factor via TEV protease site/beta-arrestin/TE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50344799(N-(4-(aminomethyl)-2,6-dimethylphenyl)-5-(2,5-dich...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of S1P2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50344799(N-(4-(aminomethyl)-2,6-dimethylphenyl)-5-(2,5-dich...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of S1P5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50344799(N-(4-(aminomethyl)-2,6-dimethylphenyl)-5-(2,5-dich...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of S1P1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed