BDBM50344875 3-((5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-1-ethylpiperidin-4-one::CHEMBL1780080

SMILES CCN1CCC(=O)C(C1)=Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1)C(F)(F)F

InChI Key InChIKey=JWMFCUROZUDFLT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50344875   

TargetProstaglandin G/H synthase 2(Sheep)
University of Mansoura

Curated by ChEMBL
LigandPNGBDBM50344875(3-((5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl...)
Affinity DataIC50: 450nMAssay Description:Inhibition of ovine COX2 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Mansoura

Curated by ChEMBL
LigandPNGBDBM50344875(3-((5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ovine COX1 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Mansoura

Curated by ChEMBL
LigandPNGBDBM50344875(3-((5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl...)
Affinity DataIC50: 450nMAssay Description:Inhibition of ovine COX2 by enzyme immuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed