BDBM50344938 (R)-1-benzyl-2-(4-fluorophenyl)-5,7-diisopropyl-7,8-dihydro-1H-imidazo[2,1-b]purin-4(5H)-one::CHEMBL1777923

SMILES CC(C)[C@@H]1CN2C(=N1)N(C(C)C)C(=O)c1nc(-c3ccc(F)cc3)n(Cc3ccccc3)c21

InChI Key InChIKey=ZLJQTWCMKRKSBV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344938   

TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344938((R)-1-benzyl-2-(4-fluorophenyl)-5,7-diisopropyl-7,...)
Affinity DataIC50: 470nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed