BDBM50344941 (R)-1-benzyl-2-(4-fluorophenyl)-7-isopropyl-7,8-dihydro-1H-imidazo[2,1-b]purin-4(5H)-one::CHEMBL1777920

SMILES CC(C)[C@@H]1CN2C(NC(=O)c3nc(-c4ccc(F)cc4)n(Cc4ccccc4)c23)=N1

InChI Key InChIKey=LTJSZOMSSUPBGO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344941   

TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344941((R)-1-benzyl-2-(4-fluorophenyl)-7-isopropyl-7,8-di...)
Affinity DataIC50: 1.25E+3nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed