BDBM50345409 CHEMBL1784571::N1-tert-Butyl-N4(5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)benzene-1,4-diamine

SMILES Cc1cc(Nc2ccc(NC(C)(C)C)cc2)n2ncnc2n1

InChI Key InChIKey=GBFWOKQSNLKFFT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345409   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. falciparum)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50345409(N1-tert-Butyl-N4(5-methyl-[1,2,4]triazolo[1,5-a]py...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed