BDBM50345445 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile::CHEMBL1784718

SMILES O=c1nc2c3cccc4cccc(c2c1C#N)c34

InChI Key InChIKey=VQYSTSIAUDPRJH-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345445   

TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345445(8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile |...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50345445(8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile |...)
Affinity DataKd:  1.83E+3nMAssay Description:Binding affinity to his-tagged Mcl-1 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed