BDBM50345457 CHEMBL1784729::Ethyl 8-Oxo-3-(2-(pyrazin-2-yl)ethylthio)-8H-acenaphtho[1,2-b]pyrrole-9-carboxylate

SMILES CCOC(=O)c1c2c3ccc(SCCc4cnccn4)c4cccc(c2nc1=O)c34

InChI Key InChIKey=XTUJRWNRJGZFHG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345457   

TargetFibroblast growth factor receptor 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50345457(Ethyl 8-Oxo-3-(2-(pyrazin-2-yl)ethylthio)-8H-acena...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed