BDBM50345779 2-(2-(4-(4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl)pyrimidin-2-yloxy)phenyl)acetamide::CHEMBL1785002::GSK screening, 37

SMILES NC(=O)Cc1ccccc1Oc1nccc(n1)-c1c(ncn1C1CCNCC1)-c1ccc(F)cc1

InChI Key InChIKey=IZZFCONHZHYYET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345779   

TargetSerine/threonine-protein kinase TBK1(Human)
Technical University of Dortmund

LigandPNGBDBM50345779(2-(2-(4-(4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-...)
Affinity DataIC50: 3.03E+3nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2015
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University College of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50345779(2-(2-(4-(4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-...)
Affinity DataIC50: 134nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed