BDBM50345995 1-[4-(3,5-Dimethoxy-benzylamino)phenyl]-3-phenylurea::CHEMBL1783634

SMILES COc1cc(CNc2ccc(NC(=O)Nc3ccccc3)cc2)cc(OC)c1

InChI Key InChIKey=GBELFAXEBHVADG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345995   

TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345995(1-[4-(3,5-Dimethoxy-benzylamino)phenyl]-3-phenylur...)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed