BDBM50346242 (3-(1H-pyrazol-1-yl)phenyl)(5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-1-yl)methanone::CHEMBL1782182

SMILES Oc1ccccc1C1CC(=NN1C(=O)c1cccc(c1)-n1cccn1)c1cccnc1

InChI Key InChIKey=TWIBJRRRYBAZFC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50346242   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346242((3-(1H-pyrazol-1-yl)phenyl)(5-(2-hydroxyphenyl)-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346242((3-(1H-pyrazol-1-yl)phenyl)(5-(2-hydroxyphenyl)-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346242((3-(1H-pyrazol-1-yl)phenyl)(5-(2-hydroxyphenyl)-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346242((3-(1H-pyrazol-1-yl)phenyl)(5-(2-hydroxyphenyl)-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346242((3-(1H-pyrazol-1-yl)phenyl)(5-(2-hydroxyphenyl)-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346242((3-(1H-pyrazol-1-yl)phenyl)(5-(2-hydroxyphenyl)-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KIT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed