BDBM50346281 CHEMBL1782554::sodium(3R,5R)-7-(5-cyclopropyl-2-(4-fluorophenyl)-4-(2-methylbenzylcarbamoyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate

SMILES Cc1ccccc1CNC(=O)c1nc(-c2ccc(F)cc2)n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1C1CC1

InChI Key InChIKey=GWUOIDODGYKLIT-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346281   

LigandPNGBDBM50346281(sodium(3R,5R)-7-(5-cyclopropyl-2-(4-fluorophenyl)-...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed