BDBM50346291 CHEMBL1782563::sodium(3R,5R)-7-(5-cyclopropyl-4-(3-fluoro-4-methoxybenzylcarbamoyl)-2-(4-fluorophenyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate

SMILES COc1ccc(CNC(=O)c2nc(-c3ccc(F)cc3)n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c2C2CC2)cc1F

InChI Key InChIKey=PFQZVZLGFDDIJU-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346291   

LigandPNGBDBM50346291(sodium(3R,5R)-7-(5-cyclopropyl-4-(3-fluoro-4-metho...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed