BDBM50346534 CHEMBL1797705

SMILES N[C@H]1C[C@@H]1c1cccc(OCC[C@H](NC(=O)c2ccccc2)C(=O)NCc2ccccc2)c1

InChI Key InChIKey=DTPSXFMGMQOVTG-UHFFFAOYSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50346534   

TargetLysine-specific histone demethylase 1A(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50346534(CHEMBL1797705)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of partially purified LSD1 using histone H3K4Me2 peptide substrate by peroxidase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50346534(CHEMBL1797705)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50346534(CHEMBL1797705)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of N terminal hexahistidine-tag recombinant human LSD1 expressed in Escherichia coli BL21 (DE3) using histone H3 peptide as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50346534(CHEMBL1797705)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50346534(CHEMBL1797705)
Affinity DataKi:  5.70E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50346534(CHEMBL1797705)
Affinity DataKi:  5.70E+3nMAssay Description:Inhibition of N terminal hexahistidine-tag recombinant human LSD1 expressed in Escherichia coli BL21 (DE3) using histone H3 peptide as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50346534(CHEMBL1797705)
Affinity DataKi:  2.30E+5nMAssay Description:Inhibition of MAO AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50346534(CHEMBL1797705)
Affinity DataKi:  7.40E+5nMAssay Description:Inhibition of MAO BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed