BDBM50347433 CHEMBL1801864

SMILES CC(C)=CCN(Cc1cc2c(=O)n(C)nnc2cc1Cl)c1ccc(C(=O)NCc2cccnc2)cc1

InChI Key InChIKey=RTGCXRUCOOSKJC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50347433   

TargetNicotinamide phosphoribosyltransferase(Human)
Myrexis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50347433BDBM50347433(CHEMBL1801864)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of nicotinamide phosphoribosyltransferase-catalyzed conversion of nicotinamide to nicotinamide mononucleotideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Myrexis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50347433BDBM50347433(CHEMBL1801864)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Myrexis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50347433BDBM50347433(CHEMBL1801864)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human Nampt after 3 hrs by counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed