BDBM50347563 CHEMBL1801740

SMILES CCc1nc2c(C)cc(CC(C)C)nc2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=HHFWRZYDWOGTJX-UHFFFAOYSA-N

Data  2 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50347563   

TargetType-1 angiotensin II receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50347563(CHEMBL1801740)
Affinity DataKi:  0.690nMAssay Description:Binding affinity to human Angiotensin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50347563(CHEMBL1801740)
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor afterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50347563(CHEMBL1801740)
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50347563(CHEMBL1801740)
Affinity DataEC50:  212nMAssay Description:Partial agonist activity at human PPARgamma-LBD/Gal4 DNA binding domain by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50347563(CHEMBL1801740)
Affinity DataEC50:  212nMAssay Description:Partial agonist activity at human PPARgamma-LBD/Gal4 DNA binding domain by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50347563(CHEMBL1801740)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human Angiotensin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed