BDBM50347662 CHEMBL1802913

SMILES COCCCN(C)S(=O)(=O)Nc1ccc2ccc3ncc(cc3c(=O)c2c1)-c1cnn(C)c1

InChI Key InChIKey=NRMBCLVVHWHCEG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50347662   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50347662(CHEMBL1802913)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kv11.1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50347662(CHEMBL1802913)
Affinity DataIC50: 58nMAssay Description:Inhibition of c-MET overexpressed in human GTL-16 cells assessed as phosphorylation at C-terminal Y1349 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50347662(CHEMBL1802913)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant c-Met-catalyzed phosphorylation of N-biotinylated peptide (EQEDEPEGDYFEWLE-CONH2) by time-resolved fluorescence reson...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed