BDBM50347694 CHEMBL1802606

SMILES Cn1cc(cn1)-c1cnc2ccc3ccc(O)cc3c(=O)c2c1

InChI Key InChIKey=TUWYKTGWOOZYIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50347694   

TargetHepatocyte growth factor receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50347694(CHEMBL1802606)
Affinity DataIC50: 370nMAssay Description:Inhibition of c-MET overexpressed in human GTL-16 cells assessed as phosphorylation at C-terminal Y1349 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50347694(CHEMBL1802606)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant c-Met-catalyzed phosphorylation of N-biotinylated peptide (EQEDEPEGDYFEWLE-CONH2) by time-resolved fluorescence reson...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed