BDBM50347921 CHEMBL1802485

SMILES Cn1nc2-c3ccccc3C(=O)c3cccc1c23

InChI Key InChIKey=ODZGYELAMAOARP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50347921   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50347921(CHEMBL1802485)
Affinity DataIC50: 8.17E+3nMAssay Description:Inhibition of c-JUN in human ANBL-6 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prolife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50347921(CHEMBL1802485)
Affinity DataIC50: 8.62E+3nMAssay Description:Inhibition of c-JUN in Melphalan Resistant human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50347921(CHEMBL1802485)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of c-JUN in human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347921(CHEMBL1802485)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50347921(CHEMBL1802485)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of c-JUN in bortezomib Resistant human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50347921(CHEMBL1802485)
Affinity DataIC50: 3.24E+4nMAssay Description:Inhibition of c-JUN in human bortezomib-resistant ANBL6 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50347921(CHEMBL1802485)
Affinity DataIC50: 4.49E+4nMAssay Description:Inhibition of c-JUN in human U-266 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prolifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed