BDBM50347939 CHEMBL1800137

SMILES CC(C)(N)C(=O)N1CCn2c(C1)nc(c2Nc1ccc(F)cc1)-c1ccc(F)cc1

InChI Key InChIKey=NIFJWDNQUGBNEW-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50347939   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50347939(CHEMBL1800137)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by Q-patch assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50347939(CHEMBL1800137)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of CYP 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50347939(CHEMBL1800137)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of CYP 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50347939(CHEMBL1800137)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of CYP 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50347939(CHEMBL1800137)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of CYP 2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50347939(CHEMBL1800137)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of CYP 1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50347939(CHEMBL1800137)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human ERG channel expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50347939(CHEMBL1800137)
Affinity DataIC50: 3.95E+3nMAssay Description:Binding affinity to human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed