BDBM50349635 CHEMBL1808993

SMILES CN1CCN(C(=O)c2ccc(NC(=O)Nc3ccc(-c4nc(N5CCOCC5)[nH]c(=O)n4)cc3)cc2)CC1

InChI Key InChIKey=FMXJLJWHHSYGHH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50349635   

LigandChemical structure of BindingDB Monomer ID 50349635BDBM50349635(CHEMBL1808993)
Affinity DataIC50: 15nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50349635BDBM50349635(CHEMBL1808993)
Affinity DataIC50: 96.5nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50349635BDBM50349635(CHEMBL1808993)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed