BDBM50350167 CHEMBL1814741

SMILES N[C@@H](CC(=O)N1CCN(CC1)C(c1ccccc1)c1ccc(Cl)cc1)C(=O)N1Cc2ccccc2C1

InChI Key InChIKey=HNVDBWUDPUTVEW-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50350167   

TargetDipeptidyl peptidase 8(Human)
University of Antwerp (Ua)

Curated by ChEMBL
LigandPNGBDBM50350167(CHEMBL1814741)
Affinity DataKi:  6.5nMAssay Description:Competitive inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
University of Antwerp (Ua)

Curated by ChEMBL
LigandPNGBDBM50350167(CHEMBL1814741)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp (Ua)

Curated by ChEMBL
LigandPNGBDBM50350167(CHEMBL1814741)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Antwerp (Ua)

Curated by ChEMBL
LigandPNGBDBM50350167(CHEMBL1814741)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human seminal plasma DPP4 assessed as pNA release from Gly-Pro-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed