BDBM50350388 CHEMBL1813474

SMILES Clc1ccc(cc1Cl)[C@]12CCC[C@H]1CNC2

InChI Key InChIKey=ZOSQXAHBYHMVCA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50350388   

TargetCytochrome P450 2C19(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50350388(CHEMBL1813474)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50350388(CHEMBL1813474)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50350388(CHEMBL1813474)
Affinity DataIC50: 4.01E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50350388(CHEMBL1813474)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by high throughput single cell planar patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50350388(CHEMBL1813474)
Affinity DataIC50: 9.17E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed