BDBM50350507 CHEMBL1814813

SMILES CNS(=C)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1

InChI Key InChIKey=MBTYZIYXBKABHQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50350507   

TargetProstaglandin G/H synthase 1(Human)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50350507(CHEMBL1814813)
Affinity DataIC50: 42nMAssay Description:Inhibition of human platelets COX1 assessed as PGE2 production using arachidonic acid as substrate preincubated for 15 mins measured after 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50350507(CHEMBL1814813)
Affinity DataIC50: 156nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as PGE2 production using arachidonic acid as substrate preincubated for 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50350507(CHEMBL1814813)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as inhibition of tail current at holding potential of -70 mV after 10 mins by whole-cell p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed