BDBM50351253 CHEMBL1818528

SMILES COc1ccc(cc1)C(SC[C@@H](N)CO)(c1ccccc1)c1ccccc1

InChI Key InChIKey=WKYHDWRETJHQFE-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50351253   

TargetKinesin-like protein KIF11(Human)
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM50351253(CHEMBL1818528)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM50351253(CHEMBL1818528)
Affinity DataEC50:  160nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed