BDBM50351498 CHEMBL1819625

SMILES COc1ccc(NC(=O)c2ccc(OC[C@@H]3CN(C)c4ccccc4O3)cc2Cl)cc1CC(O)=O

InChI Key InChIKey=HMYLRZCRBNWSRN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50351498   

TargetProstaglandin D2 receptor(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351498(CHEMBL1819625)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351498(CHEMBL1819625)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]PGD2 from mouse prostanoid DP receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed