BDBM50352755 CHEMBL1823068::US8835436, Example 144

SMILES COc1ccccc1-n1c(C)nc(C(=O)NCCCN2CCN(CC2)c2cccc(Cl)c2C)c1C

InChI Key InChIKey=CPTMTPODYRWAHG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50352755   

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

US Patent
LigandPNGBDBM50352755(CHEMBL1823068 | US8835436, Example 144)
Affinity DataIC50: 12.8nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

US Patent
LigandPNGBDBM50352755(CHEMBL1823068 | US8835436, Example 144)
Affinity DataIC50: 37.4nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Green Cross

US Patent
LigandPNGBDBM50352755(CHEMBL1823068 | US8835436, Example 144)
Affinity DataIC50: 16.8nMpH: 7.4Assay Description:For serotonin transporter binding assays, a reaction mixture with a final volume of 0.25 ml was prepared by mixing a test compound, human serotonin t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

US Patent
LigandPNGBDBM50352755(CHEMBL1823068 | US8835436, Example 144)
Affinity DataIC50: 12.8nMAssay Description:Displacement of [3H]ketanserin from human recombinant serotonin 5-HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

US Patent
LigandPNGBDBM50352755(CHEMBL1823068 | US8835436, Example 144)
Affinity DataIC50: 37.4nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

US Patent
LigandPNGBDBM50352755(CHEMBL1823068 | US8835436, Example 144)
Affinity DataIC50: 16.8nMAssay Description:Displacement of [3H]impiramine from human serotonin transporter membrane expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed